This paper is relevant to the impact areas in the following areas:
| Crops | Wheat |
| Traits | Not Trait-Specific |
| Countries | Not country-specific |
| Regions | Not region-specific |
| Tags | feeding study, mice, safety, triticale |
This study was conducted to observe the effect of transgenic triticale grain feeding on the health and growth intensity of mice, and determine the presence the transgenic DNA in tissues of the mice. 91 days old C57Bl/6J mice were fed with pellets containing 20% conventional Bogo triticale grain or pellets containing 20% transgenic triticale grain obtained from the same cultivar, but resistant to BASTA herbicide with phosphonithricin as an active substance (control and experimental group, respectively). Feeding regimen (with or without transgenic triticale) was maintained continuously in both groups for 5 generations, and body weight of animals was recorded on days 21, 42, 63 and 91 of life. There were no significant inter-group body weight differences were observed. During the experiment, mice of both groups showed no pathological manifestations, were found healthy and did not produce any visible skin changes. PCR used to analyse the blood, kidneys, liver, spleen and thigh muscle of the experimental animals failed to detect the presence of transgenic DNA (PCR product of 637 bp) in any of the tissues. It is concluded that transgenic triticale used to feed the experimental group has no effect on the health and growth of mice, and that transgenic DNA does not appear in their tissues.
The effect of diet containing genetically modified triticale on growth and transgenic DNA fate in selected tissues of mice (held on an external server, and so may require additional authentication details)
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