Malnutrition has been one of the major global health problems mainly in underdeveloped and developing world causing massive economic damage as well as distressing human life. Deficiency of useful micronutrients like vitamins and minerals including low level of availability of better quality protein causes hidden hunger which can be alleviate with the help of genetic biofortification of crops. Besides all the challenges, biofortified maize crops like quality protein maize along with the provitamin A and Zn hold a great future to address the malnutrition challenge combating the deficiency of malnutrtients. This is the most sustainable, cost-effective and potentially wide reaching approach which can bridge the gap between agriculture and nutrition. Biofortification can be achieved both by agronomic and genetic approaches. The Importance, genetics and potential of biofortification is thoroughly reviewed to provide useful findings for new readers and researchers.