This paper is relevant to the impact areas in the following areas:
| Crops | |
| Traits | |
| Countries | |
| Regions | |
| Tags | 1 Synthetic Biology |
We report the design, synthesis, and assembly of the 1.08-mega-base pair Mycoplasma mycoides JCVI-syn1.0 genome starting from digitized genome sequence information and its transplantation into a M. capricolum recipient cell to create new M. mycoides cells that are controlled only by the synthetic chromosome. The only DNA in the cells is the designed synthetic DNA sequence, including “watermark” sequences and other designed gene deletions and polymorphisms, and mutations acquired during the building process. The new cells have expected phenotypic properties and are capable of continuous self-replication.
Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome (held on an external server, and so may require additional authentication details)
CropLife International fully acknowledges the source and authors of the publication as detailed above.