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| Tags | 1 Synthetic Biology |
Ethnopharmacological relevance
Malaria is among the most prevalent infectious diseases in the developing countries of world. Estimated number of annual malaria episodes in Pakistan is 1.5 million, but very little is known about medicinal plant species of Pakistan, which have great potential against malarial disease. Present study was aimed to document medicinal plant species used by the local inhabitants of Lesser Himalayas–Pakistan to treat malaria.
Materials and methods
Data were collected through interviews, questionnaires and contributor observation. A total of 55 informants aged between 25 and 80 years who were familiar with malarial disease participated in the survey.
Results
A total of 84 plant species belonging to 69 genera and 50 families were recorded to treat malaria. Asteraceae was found as most cited botanical family with (11.9%) representation, followed by Lamiaceae (5.9%), Solanaceae and Verbenaceae (4.7%) and Violaceae (3.5%) respectively. About 60% of the inhabitants prefer herbal treatment by local herbalists or self-treatment with locally available medicinal plant species. Of the plants identified during present investigation against malaria, Azadirachta indica, Swertia chirayita and Swertia ciliata exhibited uppermost frequency of encounter (36.3%) and corresponding PR value 5. About 67.2% of the botanical taxa are reported for the first time in the treatment of malaria. It was observed thatover harvesting is the foremost threat to medicinal plant species of the study area.
Conclusion
Present survey indicates that traditional knowledge about the use of plant species against various diseases and particularly to treat malaria is in decline. Similarly anthropogenic pressure, over exploitation and grazing of the botanical taxa are the major concerns regarding medicinal plant biodiversity loss. Frequently utilized plant species with significant malarial reduction should be authenticated by in vitro and in vivo standard tests
Traditional uses of medicinal plants against malarial disease by the tribal communities of Lesser Himalayas–Pakista (held on an external server, and so may require additional authentication details)
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